Tough on Duchenne. So it's easier to be him.

Why AGAMREE®?

AGAMREE is approved to treat Duchenne muscular dystrophy (DMD) in patients as young as 2 years of age

Designed to uncouple its anti-inflammatory effects from certain side effects

Clinically proven to improve muscle strength and function in boys with DMD and was well tolerated in clinical studies

Available as a once-daily, orange-flavored oral suspension

AGAMREE Patient Brochure

Download an educational brochure to help answer any questions you may have about AGAMREE

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About AGAMREE

AGAMREE was developed to uncouple the anti-inflammatory effects of corticosteroids commonly used in DMD from certain side effects

AGAMREE is…

Group 15

A Corticosteroid With a Novel Structure

AGAMREE is structurally unique compared with corticosteroids commonly used to treat DMD

1.0-anti-inflammatory-icon

Designed to Retain Strong Anti-Inflammatory Action

Like corticosteroids commonly used to treat DMD, AGAMREE inhibits the activity of a protein complex that is an important factor in the inflammatory process

While the way AGAMREE works to treat DMD is not fully understood, it is thought that AGAMREE treats DMD through its strong anti-inflammatory action

Effectiveness in Clinical Studies

AGAMREE is clinically proven to improve muscle strength and function in boys living with DMD

Study Design

Study 1 included 121 male patients with DMD (ages 4 to less than 7 years) who were randomly assigned to be treated with AGAMREE 6 mg/kg/day (n=30), AGAMREE 2 mg/kg/day (n=30), prednisone 0.75 mg/kg/day (n=31), or placebo/sugar pill (n=30) for 24 weeks. The primary measure of muscle strength and function was the Time to Stand Test (TTSTAND) speed.

AGAMREE 6 mg/kg/day Improved Muscle Strength and Function
Boys treated with AGAMREE 6 mg/kg/day…
1.0-6mg-growers-stand

Time to Stand Test

(How fast a patient can stand
from lying on their back)

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6-Minute Walk Test

(Distance a patient can walk
in 6 minutes)

1.0-6mg-growers-faster

Time to Run/Walk 10 Meters

(How fast a patient can run or
walk 10 meters)

*Compared to placebo (sugar pill).

Side Effects With AGAMREE in Clinical Studies

What are the most common side effects associated with AGAMREE?

In clinical studies in boys living with DMD, the most common side effects with AGAMREE treatment included facial puffiness or cushingoid features, psychiatric disorders, vomiting, weight gain, and vitamin D deficiency. These are not all the possible side effects of AGAMREE.

Call your healthcare provider for medical advice about side effects.

aIncludes the following adverse reactions that occurred more frequently in the AGAMREE group than in placebo: abnormal behavior, aggression, agitation, anxiety, irritability, mood altered, sleep disorder, and stereotypy.

Table showing side effects that occurred in at least 5% of patients treated with AGAMREE and more frequently than placebo

* Includes the following adverse reactions that occurred more frequently in the AGAMREE group than in placebo: abnormal behavior, aggression, agitation, anxiety, irritability, mood altered, sleep disorder, and stereotypy.

Learn How to Start AGAMREE

Learn about getting started on AGAMREE, including dosing and administration

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Learn About Patient Support for AGAMREE

Catalyst Pathways® offers a range of free, personalized support and services

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